Early growth response protein 2
WebEarly growth response proteins are a family of zinc finger transcription factors. [1] Members of the family include: EGR1, EGR2, EGR3 and EGR4. WebMar 21, 2024 · Early Growth Response Alpha 2; Early Growth Response-Alpha 3; TIEG-1 4; External Ids for KLF10 Gene. HGNC: 11810; NCBI Entrez Gene: 7071; Ensembl: ENSG00000155090; OMIM®: 601878; ... Transforming growth factor-beta-inducible early growth response protein 1 (KLF10_HUMAN) Graphical View of Domain Structure for …
Early growth response protein 2
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WebMar 24, 2024 · 2 Cancer Center, The First Hospital of Jilin University, Changchun, China. Early growth response factor 1 (EGR1) is a transcription factor that is mainly involved in the processes of tissue injury, immune responses, and fibrosis. Recent studies have shown that EGR1 is closely related to the initiation and progression of cancer and may ... WebAs outlined earlier, sex steroids regulate the expression of early response genes within 30 minutes to 2 hours following hormone exposure. ... This notion has been strengthened by …
WebAug 1, 2024 · Using low-stringency hybridization with an EGR1 ( 128990) cDNA probe, Joseph et al. (1988) identified a distinct human cDNA, designated EGR2 (early growth response gene-2). The cDNA sequence predicts a protein of 406 amino acids, including 3 tandem zinc fingers of the cys (2)-his (2) class. The deduced amino acid sequences of … WebF The Egr1-Deficient Model. Early growth response protein 1 (Egr1) is a transcription factor that is rapidly induced by growth factors, cytokines, and stress signals such as radiation, injury, or mechanical stress to transduce signals to the downstream cascades, which is involved in cell proliferation and apoptosis regulation.
WebOct 30, 2024 · The retrograde signaling molecules of overexpression ATF-5, SIRT3, CREB, SOD1, SOD2, early growth response protein 1 (EGR1), ATF2, CCAAT/enhancer-binding protein-d, and CHOP also involved in the process. Targeted blockage of the UPRmt pathway could obviously inhibit tumor proliferation and metastasis. This review indicates … WebApr 4, 2024 · E3 SUMO-protein ligase EGR2, E3 SUMO-protein transferase ERG2, KROX-20, Drosophila, homolog (early growth response-2), early growth response protein 2, zinc finger protein Krox-20. GeneRIFs: Gene References Into Functions. EGR2-related mixed demyelinating and axonal Charcot-Marie-Tooth disease: An electrodiagnostic, …
WebApr 12, 2024 · Background: Tocotrienol, a type of vitamin E, is well known for its anti-cancer and other biological activities. This systematic review aims to summarize the involvement of endoplasmic reticulum stress (ERS) and subsequent unfolded protein response (UPR) as the underlying molecular mechanisms for the anticancer properties of tocotrienol. …
WebMay 1, 2013 · Early growth response protein 4. Gene. EGR4. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 589. Protein existence. Evidence at protein level. Annotation score. 5/5. ... C2H2-type 2 PROSITE-ProRule annotation. BLAST Add. Sequence: FQCRICLRNFSRSDHLTTHVRTH: Zinc finger: 541 … open house in monroe township njWebMar 21, 2024 · EGR2 (Early Growth Response 2) is a Protein Coding gene. Diseases associated with EGR2 include Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessiveand Charcot-Marie-Tooth … iowa state university jobs postingWebJul 19, 2003 · E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 transcriptional activity. 1 publication. ... Early growth response protein 2 (EGR-2) Zinc finger protein Krox-20; Gene names. Name. EGR2. Synonyms. KROX20. Organism names. Organism. Homo … open house inverell this weekendWebNov 18, 2014 · Abstract. Early growth response 2 (EGR2) transcription factor negatively regulates T-cell activation, in contrast to the positive regulation of this process by … iowa state university jobs boardWebThe patients with EGR2 mutations show variable clinical severity of myelinopathy including congenital hypomyelinating neuropathy, DSD and CMT1. The observed … open house invitation emailWebThe overall growth-related protein trend suggests a shift in biological processes that favour survival rather than growth within OP. The mixed response of underexpression of PPD6 but overexpression of TRXM suggested that the ROS levels were being carefully modulated under RPW infestation. iowa state university jobs iowaWebGum Arabic (GA) belongs to the Fabaceae family and contains indigestible soluble fibers (80–85%) that could be fermented by commensal bacteria to enhance performance, immune response, and intestinal integrity. This study aimed to investigate the effects of GA on performance, serum biochemical indicators, microbiota, immune-related gene … iowa state university law school