Cisplatin hyponatriämie

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August undefined, 2024

WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignancies. 1,2 Approximately 20% of all cancer patients are prescribed platinum-based chemotherapeutics. 3 Although considered highly effective, cisplatin is also a dose-dependent nephrotoxin, … WebCisplatin, a formidable anticancer treatment, is used for several varieties of cancer. There are, however, many cases in which treatment must be abandoned due to a decrease in …

Cisplatin induced hyponatremia; looking deeper - Renal …

WebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt wasting syndrome (RSWS) [1]. It is unclear why it occurs but it is believed that pharmacogenetics plays an essential role. WebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt … design papers of writing an arcticle

Cisplatin - StatPearls - NCBI Bookshelf

WebApr 27, 2024 · Hyponatremia is a common adverse effect induced by cisplatin. Caution should be exercised with patients with a low sodium level before starting chemotherapy. Hyponatremia can be associated with other chemotherapy-related adverse effects, and it should therefore be treated correctly. Introduction WebNational Center for Biotechnology Information WebJun 2, 2024 · Group A received cisplatin 60-100 mg/m 2 q 3 weeks with laboratories before day 1, group B received cisplatin 60-75 mg/m 2 q 3 weeks with laboratories before days 1 and 8 of each cycle and group C had weekly cisplatin 40 mg/m 2 and laboratories. Association between hypomagnesemia, hypokalemia, hyponatremia, and risk of AKI, as … chuck e cheese locations il

Cisplatin induced hyponatremia; looking deeper - Renal

WebKeywords: Cisplatin, Dehydration, Hyponatremia, Renal salt wasting, Siadh. Case Presentation: A 63-year-old male presents to the hospital with complaints of one-day history of weakness, dizziness. His outpatient blood work demonstrated a serum sodium level of 124 mEq/L, and a creatinine of 3.1 mg/dL. His medical history was significant for high ... Webmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less. design paint walls for roomsWebJan 1, 2024 · Hyponatremia in cancer patients can be caused by a number of factors including gastrointestinal losses, cardiac failure, diabetes insipidus, cancer-induced physiological changes or hormonal secretion, pulmonary diseases, central nervous system disorders, several drugs other than anticancer treatments (e.g., chlorpropamide, … design path studios

"WebNov 1, 1997 · Cisplatin is one of the most widely used agents in cancer treatment. Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of … " - Cisplatin hyponatriämie

Cisplatin hyponatriämie

Cisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome ...

WebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated with a sodium supplement. We also summarize the key diagnostic features and the most common differential diagnoses for hyponatremia syndrome. WebHyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) or gastrointestinal loss of sodium is sometimes seen during chemotherapy. However, …

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WebNational Center for Biotechnology Information WebJun 11, 2024 · INTRODUCTION Hyponatremia represents a relative excess of water in relation to sodium. It can be induced by a marked increase in water intake (primary polydipsia) and/or by impaired water excretion due, for example, to advanced kidney failure or persistent release of antidiuretic hormone (ADH). (See "Causes of hypotonic …

Webwhich can induce hyponatremia. As regards platinum, cisplatin is more frequently described than carbopla-tin.[1] The incidence of hyponatremia secondary to cisplatin can be as high as 43%,[6] the mechanism of action by which cisplatin induces hyponatremia is 100 105 110 115 120 125 130 135 140 0 100 200 300 400 500 600 Na + urine (ml/H) … WebHyponatremia was defined and graded using the Common Terminology Criteria for Adverse Events, version 4.0, as follows: a serum sodium concentration from lower limit of normal to 130 mEq/L, grade 1; …

WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are common side effects of platinum … WebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis …

WebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated …

WebOnset of severe hyponatremia following cisplatin (CDDP) administration has been previously reported. However, the risk factors associated with hyponatremia still remain … design partnership nairobiWebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt … design pattern factory javaWebCisplatin-induced hyponatremia and renal sodium wast-ing. Acta Oncol 1995;34:264-5. 12. Cao L, Joshi P, Sumoza D. Renal salt-wasting syndrome in a patient with cisplatin-induced hyponatremia. Am J design pattern adapter pythonWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with ... design pattern dependency injection design patent inventorshipWebOct 25, 1997 · Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of cases due to salt wasting with hypomagnesemia and normokaliemia. Functional and renal failure and orthostatic hypotension can be observed. Case report: Hyponatremia with confusion occurred after each cisplatin perfusion. design patent wiping cloth makeupWebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia. * hypomagnesemia. … chuck e cheese locations in oregon