WebAug 26, 2024 · Circular EIF4G3 (CircEIF4G3; hSA_CIRC_0007991) is downregulated in gastric cancer tissues and is associated with poor clinical prognosis. Overexpression of … WebAug 26, 2024 · CircEIF4G3 is expected to be a biomarker and therapeutic target for predicting the prognosis of gastric cancer. By analyzing the Master Gene Expression (GEO) dataset, we identified circRNAs that are differentially expressed in GCs. The researchers explored the biological role of circRNAs in GC through in vitro functional analysis and in …
CircEIF4G3 overexpression attenuates GC growth and
Webcells Article SRRM4 Expands the Repertoire of Circular RNAs by Regulating Microexon Inclusion Vanessa M. Conn 1,2, Marta Gabryelska 1,2, Shashikanth Marri 1,2, Brett W. Stringer 1,2,3, Rebecca J. Ormsby 1,2, Timothy Penn 1,2, Santosh Poonnoose 2,4, Ganessan Kichenadasse 2,5 and Simon J. Conn 1,2,* 1 Flinders Cancer Research, … WebBiogenesis Inc me circrna biogenesis factor Me Circrna Biogenesis Factor, supplied by Biogenesis Inc, used in various techniques. Bioz Stars score: 92/100, based on 3 PubMed citations. grace church md
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WebThe results showed that the expressions of circDDX17, Has_circ_0026344, circVAPA, circNSUN2, circACAP2, circACVRL1 and circEIF4G3 were regulated by 0.8 mmol/L ALO (p<0.001, Figure 3A). Through subsequent screening of target genes, we found that only circNSUN2 and miR-296-5p have targeted binding sites . WebJul 2, 2024 · CircEIF4G3 expression was downregulated in patients with GC and predicted poor prognosis. CircEIF4G3 destabilized δ-catenin by forming circEIF4G3/δ … WebResults Downregulated expression of circular RNA EIF4G3 (circEIF4G3; hsa_circ_0007991) was found in GC and was associated with poor clinical outcomes. Overexpression of circEIF4G3 suppressed GC growth and metastasis through the inhibition of β-catenin signaling, whereas knockdown of circEIF4G3 showed the opposite effects. grace church mcarthur